Francis I of France

Siblings
1. Marguerite, Queen of Navarre  (1492-1549) (57 years)

Grandchildren via Henry I, Duke of Brittany/II, King of France
1. Francis II, King of France  (1544-60) (60 years)

2. Elisabeth, Queen of Spain and Portugal  (1545-68) (23 years)

3. Claude, Duchess of Lorraine  (1547-75) (28 years)

4. Louis III, Duke of Orléans  (1549-50) (1 year)

5. Charles IX, King of France  (1550-74) (24 years)

6. Henry III, King of Poland/III, King of France  (1551-89) (38 years)

7. Margaret, Queen of Navarre and France  (1553-1615) (62 years)

8. Francis, Duke of Anjou  (1555-84) (29 years)

9. Victoria, Princess of Valois  (1556-56) (1 month)

10. Joan, Princess of Valois  (1556-56) (1 day)

Grandchildren via Margaret, Duchess of Berry
1. Charles Emmanuel I, Duke of Savoy  (1562-1630) (68 years)